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The NF-κB Transcription Factor c-Rel Modulates Group 2 Innate Lymphoid Cell Effector Functions and Drives Allergic Airway Inflammation
Group 2 innate lymphoid cells (ILC2s) play a key role in the initiation and orchestration of early type 2 immune responses. Upon tissue damage, ILC2s are activated by alarmins such as IL-33 and rapidly secrete large amounts of type 2 signature cytokines. ILC2 activation is governed by a network of t...
Autores principales: | Mindt, Barbara C., Krisna, Sai Sakktee, Duerr, Claudia U., Mancini, Mathieu, Richer, Lara, Vidal, Silvia M., Gerondakis, Steven, Langlais, David, Fritz, Jörg H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635195/ https://www.ncbi.nlm.nih.gov/pubmed/34867937 http://dx.doi.org/10.3389/fimmu.2021.664218 |
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