Cargando…

Early Low Level of Procalcitonin Is Associated with a Favorable Outcome in a Case of a Surviving Patient with 80% Body Surface Area Thermal Burn

Patient: Male, 28-year-old Final Diagnosis: Burn wound Symptoms: Pain • dyspnea Medication: — Clinical Procedure: — Specialty: Anesthesiology • Critical Care Medicine • Surgery OBJECTIVE: Unusual clinical course BACKGROUND: Burns covering a large skin surface area represent a life-threatening condit...

Descripción completa

Detalles Bibliográficos
Autores principales: Pavel, Bogdan, Popescu, Mihaela Roxana, Skolozubova, Daria, Flutur, Elena, Voiculescu, Vlad Mihai, Brezeanu, Ariana Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635220/
https://www.ncbi.nlm.nih.gov/pubmed/35642541
http://dx.doi.org/10.12659/AJCR.934052
_version_ 1784608258873360384
author Pavel, Bogdan
Popescu, Mihaela Roxana
Skolozubova, Daria
Flutur, Elena
Voiculescu, Vlad Mihai
Brezeanu, Ariana Cristina
author_facet Pavel, Bogdan
Popescu, Mihaela Roxana
Skolozubova, Daria
Flutur, Elena
Voiculescu, Vlad Mihai
Brezeanu, Ariana Cristina
author_sort Pavel, Bogdan
collection PubMed
description Patient: Male, 28-year-old Final Diagnosis: Burn wound Symptoms: Pain • dyspnea Medication: — Clinical Procedure: — Specialty: Anesthesiology • Critical Care Medicine • Surgery OBJECTIVE: Unusual clinical course BACKGROUND: Burns covering a large skin surface area represent a life-threatening condition due to the release of cytokines and the activation of a systemic inflammatory response, as well as the potential for septic complications. Outcome for these patients is related to the burn surface, age, and coexisting diseases. Although some severity scores are available, such as the Abbreviated Burn Severity Index (ABSI), Baux score, R-Baux score, Boston score, and Belgian Outcome Burn Injury (BOBI) score, none can provide a solid picture of the final outcome. Recent studies claim that procalcitonin, a known sepsis marker, can assist in estimating a burn patient’s chance of survival from the time of admission, and can also assist in estimating the chance of sepsis occurrence during hospitalization. CASE REPORT: In this manuscript we report the case of a 28-year-old man who suffered burn injuries on approximately 80% of his body surface due to poor handling of a gasoline can in August 2018. Despite high severity index scores and early high values of C-reactive protein, we noticed a low level of early procalcitonin. In this case, as well in our previous experience, early low procalcitonin was associated with a favorable outcome. CONCLUSIONS: Early procalcitonin values might prove to be a promising prognosis marker in some cases of extensive burns.
format Online
Article
Text
id pubmed-8635220
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher International Scientific Literature, Inc.
record_format MEDLINE/PubMed
spelling pubmed-86352202021-12-16 Early Low Level of Procalcitonin Is Associated with a Favorable Outcome in a Case of a Surviving Patient with 80% Body Surface Area Thermal Burn Pavel, Bogdan Popescu, Mihaela Roxana Skolozubova, Daria Flutur, Elena Voiculescu, Vlad Mihai Brezeanu, Ariana Cristina Am J Case Rep Articles Patient: Male, 28-year-old Final Diagnosis: Burn wound Symptoms: Pain • dyspnea Medication: — Clinical Procedure: — Specialty: Anesthesiology • Critical Care Medicine • Surgery OBJECTIVE: Unusual clinical course BACKGROUND: Burns covering a large skin surface area represent a life-threatening condition due to the release of cytokines and the activation of a systemic inflammatory response, as well as the potential for septic complications. Outcome for these patients is related to the burn surface, age, and coexisting diseases. Although some severity scores are available, such as the Abbreviated Burn Severity Index (ABSI), Baux score, R-Baux score, Boston score, and Belgian Outcome Burn Injury (BOBI) score, none can provide a solid picture of the final outcome. Recent studies claim that procalcitonin, a known sepsis marker, can assist in estimating a burn patient’s chance of survival from the time of admission, and can also assist in estimating the chance of sepsis occurrence during hospitalization. CASE REPORT: In this manuscript we report the case of a 28-year-old man who suffered burn injuries on approximately 80% of his body surface due to poor handling of a gasoline can in August 2018. Despite high severity index scores and early high values of C-reactive protein, we noticed a low level of early procalcitonin. In this case, as well in our previous experience, early low procalcitonin was associated with a favorable outcome. CONCLUSIONS: Early procalcitonin values might prove to be a promising prognosis marker in some cases of extensive burns. International Scientific Literature, Inc. 2021-11-26 /pmc/articles/PMC8635220/ /pubmed/35642541 http://dx.doi.org/10.12659/AJCR.934052 Text en © Am J Case Rep, 2021 https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
Pavel, Bogdan
Popescu, Mihaela Roxana
Skolozubova, Daria
Flutur, Elena
Voiculescu, Vlad Mihai
Brezeanu, Ariana Cristina
Early Low Level of Procalcitonin Is Associated with a Favorable Outcome in a Case of a Surviving Patient with 80% Body Surface Area Thermal Burn
title Early Low Level of Procalcitonin Is Associated with a Favorable Outcome in a Case of a Surviving Patient with 80% Body Surface Area Thermal Burn
title_full Early Low Level of Procalcitonin Is Associated with a Favorable Outcome in a Case of a Surviving Patient with 80% Body Surface Area Thermal Burn
title_fullStr Early Low Level of Procalcitonin Is Associated with a Favorable Outcome in a Case of a Surviving Patient with 80% Body Surface Area Thermal Burn
title_full_unstemmed Early Low Level of Procalcitonin Is Associated with a Favorable Outcome in a Case of a Surviving Patient with 80% Body Surface Area Thermal Burn
title_short Early Low Level of Procalcitonin Is Associated with a Favorable Outcome in a Case of a Surviving Patient with 80% Body Surface Area Thermal Burn
title_sort early low level of procalcitonin is associated with a favorable outcome in a case of a surviving patient with 80% body surface area thermal burn
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635220/
https://www.ncbi.nlm.nih.gov/pubmed/35642541
http://dx.doi.org/10.12659/AJCR.934052
work_keys_str_mv AT pavelbogdan earlylowlevelofprocalcitoninisassociatedwithafavorableoutcomeinacaseofasurvivingpatientwith80bodysurfaceareathermalburn
AT popescumihaelaroxana earlylowlevelofprocalcitoninisassociatedwithafavorableoutcomeinacaseofasurvivingpatientwith80bodysurfaceareathermalburn
AT skolozubovadaria earlylowlevelofprocalcitoninisassociatedwithafavorableoutcomeinacaseofasurvivingpatientwith80bodysurfaceareathermalburn
AT fluturelena earlylowlevelofprocalcitoninisassociatedwithafavorableoutcomeinacaseofasurvivingpatientwith80bodysurfaceareathermalburn
AT voiculescuvladmihai earlylowlevelofprocalcitoninisassociatedwithafavorableoutcomeinacaseofasurvivingpatientwith80bodysurfaceareathermalburn
AT brezeanuarianacristina earlylowlevelofprocalcitoninisassociatedwithafavorableoutcomeinacaseofasurvivingpatientwith80bodysurfaceareathermalburn