Cargando…

Radical chain monoalkylation of pyridines

The monoalkylation of N-methoxypyridinium salts with alkyl radicals generated from alkenes (via hydroboration with catecholborane), alkyl iodides (via iodine atom transfer) and xanthates is reported. The reaction proceeds under neutral conditions since no acid is needed to activate the heterocycle a...

Descripción completa

Detalles Bibliográficos
Autores principales: Rieder, Samuel, Meléndez, Camilo, Dénès, Fabrice, Jangra, Harish, Mulliri, Kleni, Zipse, Hendrik, Renaud, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635225/
https://www.ncbi.nlm.nih.gov/pubmed/34976357
http://dx.doi.org/10.1039/d1sc02748d