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Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study

There continue to be conflicting data regarding the outcomes of people with HIV (PWH) who have COVID-19 infection with most studies describing the early epidemic. We present a single site experience spanning a later timeframe from the first report on January 21, 2020 to January 20, 2021 and describe...

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Autores principales: Virata, Michael D., Shenoi, Sheela V., Ladines-Lim, Joseph, Villanueva, Merceditas S., Barakat, Lydia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635326/
https://www.ncbi.nlm.nih.gov/pubmed/34851963
http://dx.doi.org/10.1371/journal.pone.0260251
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author Virata, Michael D.
Shenoi, Sheela V.
Ladines-Lim, Joseph
Villanueva, Merceditas S.
Barakat, Lydia A.
author_facet Virata, Michael D.
Shenoi, Sheela V.
Ladines-Lim, Joseph
Villanueva, Merceditas S.
Barakat, Lydia A.
author_sort Virata, Michael D.
collection PubMed
description There continue to be conflicting data regarding the outcomes of people with HIV (PWH) who have COVID-19 infection with most studies describing the early epidemic. We present a single site experience spanning a later timeframe from the first report on January 21, 2020 to January 20, 2021 and describe clinical outcomes and predictors of hospitalization among a cohort of PWH in an urban center in Connecticut, USA. Among 103 PWH with controlled HIV disease, hospitalization occurred in 33% and overall mortality was 1%. HIV associated factors (CD4 count, HIV viral suppression) were not associated with hospitalization. Chronic lung disease (OR: 3.35, 95% CI:1.28–8.72), and cardiovascular disease (OR: 3.4, 95% CI:1.27–9.12) were independently associated with hospitalization. An increasing number of non-communicable comorbidities increased the likelihood of hospitalization (OR: 1.61, 95% CI:1.22–2.13).
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spelling pubmed-86353262021-12-02 Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study Virata, Michael D. Shenoi, Sheela V. Ladines-Lim, Joseph Villanueva, Merceditas S. Barakat, Lydia A. PLoS One Research Article There continue to be conflicting data regarding the outcomes of people with HIV (PWH) who have COVID-19 infection with most studies describing the early epidemic. We present a single site experience spanning a later timeframe from the first report on January 21, 2020 to January 20, 2021 and describe clinical outcomes and predictors of hospitalization among a cohort of PWH in an urban center in Connecticut, USA. Among 103 PWH with controlled HIV disease, hospitalization occurred in 33% and overall mortality was 1%. HIV associated factors (CD4 count, HIV viral suppression) were not associated with hospitalization. Chronic lung disease (OR: 3.35, 95% CI:1.28–8.72), and cardiovascular disease (OR: 3.4, 95% CI:1.27–9.12) were independently associated with hospitalization. An increasing number of non-communicable comorbidities increased the likelihood of hospitalization (OR: 1.61, 95% CI:1.22–2.13). Public Library of Science 2021-12-01 /pmc/articles/PMC8635326/ /pubmed/34851963 http://dx.doi.org/10.1371/journal.pone.0260251 Text en © 2021 Virata et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Virata, Michael D.
Shenoi, Sheela V.
Ladines-Lim, Joseph
Villanueva, Merceditas S.
Barakat, Lydia A.
Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study
title Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study
title_full Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study
title_fullStr Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study
title_full_unstemmed Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study
title_short Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study
title_sort cumulative burden of non-communicable diseases predicts covid hospitalization among people with hiv: a one-year retrospective cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635326/
https://www.ncbi.nlm.nih.gov/pubmed/34851963
http://dx.doi.org/10.1371/journal.pone.0260251
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