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Downregulation of SFRP2 facilitates cancer stemness and radioresistance of glioma cells via activating Wnt/β-catenin signaling

Secreted frizzled-related protein 2 (SFRP2) is a glycoprotein with frizzled-like cysteine-rich domain that binds with Wnt ligands or frizzled receptors to regulate Wnt signaling. SFRP2 is frequently hypermethylated in glioma patients, and analysis of TCGA data indicates that SFRP2 is one of the most...

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Detalles Bibliográficos
Autores principales:	Wu, Quansheng, Yin, Xiaofeng, Zhao, Wenbo, Xu, Wenli, Chen, Laizhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635357/ https://www.ncbi.nlm.nih.gov/pubmed/34852024 http://dx.doi.org/10.1371/journal.pone.0260864

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