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Short- and long-term effects of a cardiac rehabilitation program in patients implanted with a left ventricular assist device

The efficacy of cardiac rehabilitation in heart-failure patients who received a left-ventricular assist device (LVAD) instead of heart transplantation (HTx) is still unclear. This study aims to evaluate whether cardiac rehabilitation is beneficial in LVAD as HTx patients in the short term and whethe...

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Autores principales: Scaglione, Anna, Panzarino, Claudia, Modica, Maddalena, Tavanelli, Monica, Pezzano, Antonio, Grati, Paola, Racca, Vittorio, Toccafondi, Anastasia, Bordoni, Bruno, Verde, Alessandro, Cartella, Iside, Castiglioni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635401/
https://www.ncbi.nlm.nih.gov/pubmed/34851984
http://dx.doi.org/10.1371/journal.pone.0259927
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author Scaglione, Anna
Panzarino, Claudia
Modica, Maddalena
Tavanelli, Monica
Pezzano, Antonio
Grati, Paola
Racca, Vittorio
Toccafondi, Anastasia
Bordoni, Bruno
Verde, Alessandro
Cartella, Iside
Castiglioni, Paolo
author_facet Scaglione, Anna
Panzarino, Claudia
Modica, Maddalena
Tavanelli, Monica
Pezzano, Antonio
Grati, Paola
Racca, Vittorio
Toccafondi, Anastasia
Bordoni, Bruno
Verde, Alessandro
Cartella, Iside
Castiglioni, Paolo
author_sort Scaglione, Anna
collection PubMed
description The efficacy of cardiac rehabilitation in heart-failure patients who received a left-ventricular assist device (LVAD) instead of heart transplantation (HTx) is still unclear. This study aims to evaluate whether cardiac rehabilitation is beneficial in LVAD as HTx patients in the short term and whether its effects in LVAD patients persist over time. Twenty-five LVAD patients were evaluated by functional and psychological tests at admission (T0) and discharge (T1) of a 4-week inpatient structured rehabilitation program, and follow-ups 3 (T2), 6 (T3), and 12 months (T4) after discharge. Twenty-five matched HTx patients were also studied from T0 to T1 to compare the improvements in the six-minute walk test (6MWT). The quality-of-life scores substantially improved in LVAD patients and the 6MWT showed the same functional recovery as in HTx patients from T0 to T1. After T1, numerous LVAD patients withdrew from the study. However, the 6MWT outcome increased further from T1 to T3, with a positive trend during the follow-ups. Hemoglobin and the ventilatory performance increased, and the psychological perception of heart-failure symptoms and pain further improved at T2. In conclusion, exercise-based rehabilitation programs provide similar beneficial effects in LVAD and HTx patients, without deterioration in LVAD patients up to 12 months after discharge.
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spelling pubmed-86354012021-12-02 Short- and long-term effects of a cardiac rehabilitation program in patients implanted with a left ventricular assist device Scaglione, Anna Panzarino, Claudia Modica, Maddalena Tavanelli, Monica Pezzano, Antonio Grati, Paola Racca, Vittorio Toccafondi, Anastasia Bordoni, Bruno Verde, Alessandro Cartella, Iside Castiglioni, Paolo PLoS One Research Article The efficacy of cardiac rehabilitation in heart-failure patients who received a left-ventricular assist device (LVAD) instead of heart transplantation (HTx) is still unclear. This study aims to evaluate whether cardiac rehabilitation is beneficial in LVAD as HTx patients in the short term and whether its effects in LVAD patients persist over time. Twenty-five LVAD patients were evaluated by functional and psychological tests at admission (T0) and discharge (T1) of a 4-week inpatient structured rehabilitation program, and follow-ups 3 (T2), 6 (T3), and 12 months (T4) after discharge. Twenty-five matched HTx patients were also studied from T0 to T1 to compare the improvements in the six-minute walk test (6MWT). The quality-of-life scores substantially improved in LVAD patients and the 6MWT showed the same functional recovery as in HTx patients from T0 to T1. After T1, numerous LVAD patients withdrew from the study. However, the 6MWT outcome increased further from T1 to T3, with a positive trend during the follow-ups. Hemoglobin and the ventilatory performance increased, and the psychological perception of heart-failure symptoms and pain further improved at T2. In conclusion, exercise-based rehabilitation programs provide similar beneficial effects in LVAD and HTx patients, without deterioration in LVAD patients up to 12 months after discharge. Public Library of Science 2021-12-01 /pmc/articles/PMC8635401/ /pubmed/34851984 http://dx.doi.org/10.1371/journal.pone.0259927 Text en © 2021 Scaglione et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Scaglione, Anna
Panzarino, Claudia
Modica, Maddalena
Tavanelli, Monica
Pezzano, Antonio
Grati, Paola
Racca, Vittorio
Toccafondi, Anastasia
Bordoni, Bruno
Verde, Alessandro
Cartella, Iside
Castiglioni, Paolo
Short- and long-term effects of a cardiac rehabilitation program in patients implanted with a left ventricular assist device
title Short- and long-term effects of a cardiac rehabilitation program in patients implanted with a left ventricular assist device
title_full Short- and long-term effects of a cardiac rehabilitation program in patients implanted with a left ventricular assist device
title_fullStr Short- and long-term effects of a cardiac rehabilitation program in patients implanted with a left ventricular assist device
title_full_unstemmed Short- and long-term effects of a cardiac rehabilitation program in patients implanted with a left ventricular assist device
title_short Short- and long-term effects of a cardiac rehabilitation program in patients implanted with a left ventricular assist device
title_sort short- and long-term effects of a cardiac rehabilitation program in patients implanted with a left ventricular assist device
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635401/
https://www.ncbi.nlm.nih.gov/pubmed/34851984
http://dx.doi.org/10.1371/journal.pone.0259927
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