Vibrational spectroscopy analysis of ligand efficacy in human M(2) muscarinic acetylcholine receptor (M(2)R)

The intrinsic efficacy of ligand binding to G protein-coupled receptors (GPCRs) reflects the ability of the ligand to differentially activate its receptor to cause a physiological effect. Here we use attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy to examine the ligand...

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Detalles Bibliográficos
Autores principales: Katayama, Kota, Suzuki, Kohei, Suno, Ryoji, Kise, Ryoji, Tsujimoto, Hirokazu, Iwata, So, Inoue, Asuka, Kobayashi, Takuya, Kandori, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635417/
https://www.ncbi.nlm.nih.gov/pubmed/34815515
http://dx.doi.org/10.1038/s42003-021-02836-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635417/
https://www.ncbi.nlm.nih.gov/pubmed/34815515
http://dx.doi.org/10.1038/s42003-021-02836-1

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