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Vibrational spectroscopy analysis of ligand efficacy in human M(2) muscarinic acetylcholine receptor (M(2)R)
The intrinsic efficacy of ligand binding to G protein-coupled receptors (GPCRs) reflects the ability of the ligand to differentially activate its receptor to cause a physiological effect. Here we use attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy to examine the ligand...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635417/ https://www.ncbi.nlm.nih.gov/pubmed/34815515 http://dx.doi.org/10.1038/s42003-021-02836-1 |