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ssDNA nanotubes for selective targeting of glioblastoma and delivery of doxorubicin for enhanced survival

Effective treatment of glioblastoma remains a daunting challenge. One of the major hurdles in the development of therapeutics is their inability to cross the blood-brain tumor barrier (BBTB). Local delivery is an alternative approach that can still suffer from toxicity in the absence of target selec...

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Detalles Bibliográficos
Autores principales: Harris, Michael A., Kuang, Huihui, Schneiderman, Zachary, Shiao, Maple L., Crane, Andrew T., Chrostek, Matthew R., Tăbăran, Alexandru-Flaviu, Pengo, Thomas, Liaw, Kevin, Xu, Beibei, Lin, Lucy, Chen, Clark C., O’Sullivan, M. Gerard, Kannan, Rangaramanujam M., Low, Walter C., Kokkoli, Efrosini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635432/
https://www.ncbi.nlm.nih.gov/pubmed/34851666
http://dx.doi.org/10.1126/sciadv.abl5872