Digenic Inheritance: Evidence and Gaps in Hemophagocytic Lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory disorder characterized by the inability to properly terminate an immune response. Familial HLH (FHLH) and related immune dysregulation syndromes are associated with mutations in the genes PRF1, UNC13D, STX11, STXBP2, LYST, AP3B1, and RA...

Descripción completa

Detalles Bibliográficos
Autores principales: Steen, Erica A., Hermiston, Michelle L., Nichols, Kim E., Meyer, Lauren K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635482/
https://www.ncbi.nlm.nih.gov/pubmed/34868048
http://dx.doi.org/10.3389/fimmu.2021.777851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635482/
https://www.ncbi.nlm.nih.gov/pubmed/34868048
http://dx.doi.org/10.3389/fimmu.2021.777851

Ejemplares similares