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In vitro-in vivo availability of metformin hydrochloride-PLGA nanoparticles in diabetic rats in a periodontal disease experimental model

CONTEXT: Metformin is an important oral anti-hyperglycemic used in diabetes. Polylactic-co-glycolic acid (PLGA) has been widely used due to its reliability in controlling the release of drugs. OBJECTIVE: This study evaluates the in vitro-in vivo availability of metformin hydrochloride-loaded polylac...

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Detalles Bibliográficos
Autores principales:	Pereira, Aline de Sousa Barbosa Freitas, de Souza Lima, Maria Laura, da Silva-Junior, Arnobio Antonio, dos Santos Silva, Emanuell, de Araújo Júnior, Raimundo Fernandes, Martins, Agnes Andrade, Alves, Jovelina Samara Ferreira, Oliveira, Artur de Santana, De Santis Ferreira, Leandro, de Araújo Costa, Emily Cintia Tossi, Guerra, Gerlane Coelho Bernardo, de Medeiros, Caroline Addison Carvalho Xavier, Brito, Gerly A. C., de Carvalho Leitao, Renata Ferreira, de Araújo, Aurigena Antunes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635670/ https://www.ncbi.nlm.nih.gov/pubmed/34808068 http://dx.doi.org/10.1080/13880209.2021.2002369

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