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Deep-Learning-Based Natural Language Processing of Serial Free-Text Radiological Reports for Predicting Rectal Cancer Patient Survival

Most electronic medical records, such as free-text radiological reports, are unstructured; however, the methodological approaches to analyzing these accumulating unstructured records are limited. This article proposes a deep-transfer-learning-based natural language processing model that analyzes ser...

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Autores principales: Kim, Sunkyu, Lee, Choong-kun, Choi, Yonghwa, Baek, Eun Sil, Choi, Jeong Eun, Lim, Joon Seok, Kang, Jaewoo, Shin, Sang Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635726/
https://www.ncbi.nlm.nih.gov/pubmed/34868947
http://dx.doi.org/10.3389/fonc.2021.747250
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author Kim, Sunkyu
Lee, Choong-kun
Choi, Yonghwa
Baek, Eun Sil
Choi, Jeong Eun
Lim, Joon Seok
Kang, Jaewoo
Shin, Sang Joon
author_facet Kim, Sunkyu
Lee, Choong-kun
Choi, Yonghwa
Baek, Eun Sil
Choi, Jeong Eun
Lim, Joon Seok
Kang, Jaewoo
Shin, Sang Joon
author_sort Kim, Sunkyu
collection PubMed
description Most electronic medical records, such as free-text radiological reports, are unstructured; however, the methodological approaches to analyzing these accumulating unstructured records are limited. This article proposes a deep-transfer-learning-based natural language processing model that analyzes serial magnetic resonance imaging reports of rectal cancer patients and predicts their overall survival. To evaluate the model, a retrospective cohort study of 4,338 rectal cancer patients was conducted. The experimental results revealed that the proposed model utilizing pre-trained clinical linguistic knowledge could predict the overall survival of patients without any structured information and was superior to the carcinoembryonic antigen in predicting survival. The deep-transfer-learning model using free-text radiological reports can predict the survival of patients with rectal cancer, thereby increasing the utility of unstructured medical big data.
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spelling pubmed-86357262021-12-02 Deep-Learning-Based Natural Language Processing of Serial Free-Text Radiological Reports for Predicting Rectal Cancer Patient Survival Kim, Sunkyu Lee, Choong-kun Choi, Yonghwa Baek, Eun Sil Choi, Jeong Eun Lim, Joon Seok Kang, Jaewoo Shin, Sang Joon Front Oncol Oncology Most electronic medical records, such as free-text radiological reports, are unstructured; however, the methodological approaches to analyzing these accumulating unstructured records are limited. This article proposes a deep-transfer-learning-based natural language processing model that analyzes serial magnetic resonance imaging reports of rectal cancer patients and predicts their overall survival. To evaluate the model, a retrospective cohort study of 4,338 rectal cancer patients was conducted. The experimental results revealed that the proposed model utilizing pre-trained clinical linguistic knowledge could predict the overall survival of patients without any structured information and was superior to the carcinoembryonic antigen in predicting survival. The deep-transfer-learning model using free-text radiological reports can predict the survival of patients with rectal cancer, thereby increasing the utility of unstructured medical big data. Frontiers Media S.A. 2021-11-17 /pmc/articles/PMC8635726/ /pubmed/34868947 http://dx.doi.org/10.3389/fonc.2021.747250 Text en Copyright © 2021 Kim, Lee, Choi, Baek, Choi, Lim, Kang and Shin https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Kim, Sunkyu
Lee, Choong-kun
Choi, Yonghwa
Baek, Eun Sil
Choi, Jeong Eun
Lim, Joon Seok
Kang, Jaewoo
Shin, Sang Joon
Deep-Learning-Based Natural Language Processing of Serial Free-Text Radiological Reports for Predicting Rectal Cancer Patient Survival
title Deep-Learning-Based Natural Language Processing of Serial Free-Text Radiological Reports for Predicting Rectal Cancer Patient Survival
title_full Deep-Learning-Based Natural Language Processing of Serial Free-Text Radiological Reports for Predicting Rectal Cancer Patient Survival
title_fullStr Deep-Learning-Based Natural Language Processing of Serial Free-Text Radiological Reports for Predicting Rectal Cancer Patient Survival
title_full_unstemmed Deep-Learning-Based Natural Language Processing of Serial Free-Text Radiological Reports for Predicting Rectal Cancer Patient Survival
title_short Deep-Learning-Based Natural Language Processing of Serial Free-Text Radiological Reports for Predicting Rectal Cancer Patient Survival
title_sort deep-learning-based natural language processing of serial free-text radiological reports for predicting rectal cancer patient survival
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635726/
https://www.ncbi.nlm.nih.gov/pubmed/34868947
http://dx.doi.org/10.3389/fonc.2021.747250
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