Monoamine Oxidase-B Inhibitor Reduction in Pro-Inflammatory Cytokines Mediated by Inhibition of cAMP-PKA/EPAC Signaling

Mucosal epithelial cell integrity is an important component of innate immunity and it protects the host from an environment rich in microorganisms. Virulence factors from Gram-negative bacteria [e.g. lipopolysaccharide (LPS)] induce significant pro-inflammatory cytokine expression. Monoamine oxidase...

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Detalles Bibliográficos
Autores principales: Putnins, Edward E., Goebeler, Verena, Ostadkarampour, Mahyar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635787/
https://www.ncbi.nlm.nih.gov/pubmed/34867348
http://dx.doi.org/10.3389/fphar.2021.741460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635787/
https://www.ncbi.nlm.nih.gov/pubmed/34867348
http://dx.doi.org/10.3389/fphar.2021.741460

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