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Selective Chemical Labeling and Sequencing of 5-Hydroxymethylcytosine in DNA at Single-Base Resolution

5-Hydroxymethylcytosine (5hmC), the oxidative product of 5-methylcytosine (5mC) catalyzed by ten-eleven translocation enzymes, plays an important role in many biological processes as an epigenetic mediator. Prior studies have shown that 5hmC can be selectively labeled with chemically modified glucos...

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Detalles Bibliográficos
Autores principales:	Li, Xiaogang, Shi, Xinxin, Gong, Yin, Guo, Wenting, Liu, Yuanrui, Peng, Chunwei, Xu, Yingchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635956/ https://www.ncbi.nlm.nih.gov/pubmed/34868220 http://dx.doi.org/10.3389/fgene.2021.749211

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