Tyrosine-Dependent Phenotype Switching Occurs Early in Many Primary Melanoma Cultures Limiting Their Translational Value

The use of patient-derived primary cell cultures in cancer preclinical assays, including drug screens and genotoxic studies, has increased in recent years. However, their translational value is constrained by several limitations, including variability that can be caused by the culture conditions. He...

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Detalles Bibliográficos
Autores principales: Najem, Ahmad, Wouters, Jasper, Krayem, Mohammad, Rambow, Florian, Sabbah, Malak, Sales, François, Awada, Ahmad, Aerts, Stein, Journe, Fabrice, Marine, Jean-Christophe, Ghanem, Ghanem E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635994/
https://www.ncbi.nlm.nih.gov/pubmed/34869032
http://dx.doi.org/10.3389/fonc.2021.780654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635994/
https://www.ncbi.nlm.nih.gov/pubmed/34869032
http://dx.doi.org/10.3389/fonc.2021.780654

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