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E2 Site Mutations in S Protein Strongly Affect Hepatitis B Surface Antigen Detection in the Occult Hepatitis B Virus

The mechanism of occult hepatitis B infection (OBI) has not yet been fully clarified. Our previous research found that novel OBI-related mutation within S protein, E2G, could cause the hepatitis B surface antigen (HBsAg) secretion impairment, which resulted in intracellular accumulation in OBI of ge...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Liao, Fenfang, Xie, Junmo, Gao, Wenbo, Wang, Min, Huang, Jieting, Xu, Ru, Liao, Qiao, Shan, Zhengang, Zheng, Yourong, Rong, Xia, Li, Chengyao, Fu, Yongshui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635997/
https://www.ncbi.nlm.nih.gov/pubmed/34867835
http://dx.doi.org/10.3389/fmicb.2021.664833