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E2 Site Mutations in S Protein Strongly Affect Hepatitis B Surface Antigen Detection in the Occult Hepatitis B Virus
The mechanism of occult hepatitis B infection (OBI) has not yet been fully clarified. Our previous research found that novel OBI-related mutation within S protein, E2G, could cause the hepatitis B surface antigen (HBsAg) secretion impairment, which resulted in intracellular accumulation in OBI of ge...
Autores principales: | Wang, Hao, Liao, Fenfang, Xie, Junmo, Gao, Wenbo, Wang, Min, Huang, Jieting, Xu, Ru, Liao, Qiao, Shan, Zhengang, Zheng, Yourong, Rong, Xia, Li, Chengyao, Fu, Yongshui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635997/ https://www.ncbi.nlm.nih.gov/pubmed/34867835 http://dx.doi.org/10.3389/fmicb.2021.664833 |
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