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The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention

Inflammation and nutrition as main factors can affect the prognosis of patients with chronic total coronary occlusion (CTO) undergoing percutaneous coronary intervention (PCI). The C-reactive protein to albumin ratio (CAR) can clarify the inflammation and nutrition status, which are highly related t...

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Autores principales: Cheng, Lele, Meng, Zixuan, Wang, Qi, Jian, Zhijie, Fan, Pengcheng, Feng, Xinxin, Qiao, Xiangrui, Yang, Jian, Yuan, Zuyi, Li, Bolin, Wu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636141/
https://www.ncbi.nlm.nih.gov/pubmed/34869630
http://dx.doi.org/10.3389/fcvm.2021.731261
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author Cheng, Lele
Meng, Zixuan
Wang, Qi
Jian, Zhijie
Fan, Pengcheng
Feng, Xinxin
Qiao, Xiangrui
Yang, Jian
Yuan, Zuyi
Li, Bolin
Wu, Yue
author_facet Cheng, Lele
Meng, Zixuan
Wang, Qi
Jian, Zhijie
Fan, Pengcheng
Feng, Xinxin
Qiao, Xiangrui
Yang, Jian
Yuan, Zuyi
Li, Bolin
Wu, Yue
author_sort Cheng, Lele
collection PubMed
description Inflammation and nutrition as main factors can affect the prognosis of patients with chronic total coronary occlusion (CTO) undergoing percutaneous coronary intervention (PCI). The C-reactive protein to albumin ratio (CAR) can clarify the inflammation and nutrition status, which are highly related to clinical outcomes. This study aims to investigate the association between CAR and adverse cardiovascular events in patients with CTO undergoing PCI. For this study, 664 patients were divided into three groups based on the tertiles of CAR. The primary endpoint was all-cause mortality and the secondary endpoint was major adverse cardiovascular events (MACE). Over a median follow-up of 33.7 months, the primary endpoint occurred in 64 patients (9.6%) and the secondary endpoint occurred in 170 patients (25.6%). The patients with higher CAR represented a worse prognosis with all-cause death and cardiovascular death after the adjustment for the baseline risk factors. Adding the CAR values raised the predictive value for the incidence of the all-cause death and cardiovascular death but not MACE. The capacity of prognosis prediction was improved after the addition of the CAR value to the traditional prediction model.
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spelling pubmed-86361412021-12-02 The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention Cheng, Lele Meng, Zixuan Wang, Qi Jian, Zhijie Fan, Pengcheng Feng, Xinxin Qiao, Xiangrui Yang, Jian Yuan, Zuyi Li, Bolin Wu, Yue Front Cardiovasc Med Cardiovascular Medicine Inflammation and nutrition as main factors can affect the prognosis of patients with chronic total coronary occlusion (CTO) undergoing percutaneous coronary intervention (PCI). The C-reactive protein to albumin ratio (CAR) can clarify the inflammation and nutrition status, which are highly related to clinical outcomes. This study aims to investigate the association between CAR and adverse cardiovascular events in patients with CTO undergoing PCI. For this study, 664 patients were divided into three groups based on the tertiles of CAR. The primary endpoint was all-cause mortality and the secondary endpoint was major adverse cardiovascular events (MACE). Over a median follow-up of 33.7 months, the primary endpoint occurred in 64 patients (9.6%) and the secondary endpoint occurred in 170 patients (25.6%). The patients with higher CAR represented a worse prognosis with all-cause death and cardiovascular death after the adjustment for the baseline risk factors. Adding the CAR values raised the predictive value for the incidence of the all-cause death and cardiovascular death but not MACE. The capacity of prognosis prediction was improved after the addition of the CAR value to the traditional prediction model. Frontiers Media S.A. 2021-11-12 /pmc/articles/PMC8636141/ /pubmed/34869630 http://dx.doi.org/10.3389/fcvm.2021.731261 Text en Copyright © 2021 Cheng, Meng, Wang, Jian, Fan, Feng, Qiao, Yang, Yuan, Li and Wu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Cheng, Lele
Meng, Zixuan
Wang, Qi
Jian, Zhijie
Fan, Pengcheng
Feng, Xinxin
Qiao, Xiangrui
Yang, Jian
Yuan, Zuyi
Li, Bolin
Wu, Yue
The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
title The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
title_full The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
title_fullStr The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
title_full_unstemmed The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
title_short The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
title_sort usefulness of c-reactive protein to albumin ratio in the prediction of adverse cardiovascular events in coronary chronic total occlusion undergoing percutaneous coronary intervention
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636141/
https://www.ncbi.nlm.nih.gov/pubmed/34869630
http://dx.doi.org/10.3389/fcvm.2021.731261
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