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Maintenance of Complex Trait Variation: Classic Theory and Modern Data
Numerous studies have found evidence that GWAS loci experience negative selection, which increases in intensity with the effect size of identified variants. However, there is also accumulating evidence that this selection is not entirely mediated by the focal trait and contains a substantial pleiotr...
Autores principales: | Koch, Evan M., Sunyaev, Shamil R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636146/ https://www.ncbi.nlm.nih.gov/pubmed/34868244 http://dx.doi.org/10.3389/fgene.2021.763363 |
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