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Mechanistic Insights From Single-Molecule Studies of Repair of Double Strand Breaks
DNA double strand breaks (DSBs) are among some of the most deleterious forms of DNA damage. Left unrepaired, they are detrimental to genome stability, leading to high risk of cancer. Two major mechanisms are responsible for the repair of DSBs, homologous recombination (HR) and nonhomologous end join...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636147/ https://www.ncbi.nlm.nih.gov/pubmed/34869333 http://dx.doi.org/10.3389/fcell.2021.745311 |