Simultaneous Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Gene Mutations

Genetic channelopathies can predispose individuals to life-threatening arrhythmias. Two such channelopathies are long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT). To the best of our knowledge, we present the first case of LQTS with novel combined genetic mutat...

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Detalles Bibliográficos
Autores principales: Lakhana, Muhddesa, McGee, James, George, Blessen, Whang, William, Kanner, Lawrence, Park, Won Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636151/
https://www.ncbi.nlm.nih.gov/pubmed/34873534
http://dx.doi.org/10.7759/cureus.19195
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author Lakhana, Muhddesa
McGee, James
George, Blessen
Whang, William
Kanner, Lawrence
Park, Won Jun
author_facet Lakhana, Muhddesa
McGee, James
George, Blessen
Whang, William
Kanner, Lawrence
Park, Won Jun
author_sort Lakhana, Muhddesa
collection PubMed
description Genetic channelopathies can predispose individuals to life-threatening arrhythmias. Two such channelopathies are long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT). To the best of our knowledge, we present the first case of LQTS with novel combined genetic mutations of KCNH2 and cardiac ryanodine receptor (RYR2) genes.
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spelling pubmed-86361512021-12-05 Simultaneous Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Gene Mutations Lakhana, Muhddesa McGee, James George, Blessen Whang, William Kanner, Lawrence Park, Won Jun Cureus Cardiology Genetic channelopathies can predispose individuals to life-threatening arrhythmias. Two such channelopathies are long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT). To the best of our knowledge, we present the first case of LQTS with novel combined genetic mutations of KCNH2 and cardiac ryanodine receptor (RYR2) genes. Cureus 2021-11-01 /pmc/articles/PMC8636151/ /pubmed/34873534 http://dx.doi.org/10.7759/cureus.19195 Text en Copyright © 2021, Lakhana et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Lakhana, Muhddesa
McGee, James
George, Blessen
Whang, William
Kanner, Lawrence
Park, Won Jun
Simultaneous Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Gene Mutations
title Simultaneous Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Gene Mutations
title_full Simultaneous Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Gene Mutations
title_fullStr Simultaneous Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Gene Mutations
title_full_unstemmed Simultaneous Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Gene Mutations
title_short Simultaneous Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Gene Mutations
title_sort simultaneous catecholaminergic polymorphic ventricular tachycardia and long qt syndrome gene mutations
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636151/
https://www.ncbi.nlm.nih.gov/pubmed/34873534
http://dx.doi.org/10.7759/cureus.19195
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