Hexokinases II‐mediated glycolysis governs susceptibility to crizotinib in ALK‐positive non‐small cell lung cancer

BACKGROUND: Activation of ALK leads to a high level of aerobic glycolysis related to crizotinib insensitivity in anaplastic lymphoma kinase‐positive non‐small cell lung cancer (ALK(+) NSCLC). The strategy and mechanism of glycolysis inhibition in sensitizing ALK(+) NSCLC cells to crizotinib requires...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Caiyu, Chen, Hengyi, Han, Rui, Li, Li, Lu, Conghua, Hao, Shuai, Wang, Yubo, He, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636216/
https://www.ncbi.nlm.nih.gov/pubmed/34729938
http://dx.doi.org/10.1111/1759-7714.14184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636216/
https://www.ncbi.nlm.nih.gov/pubmed/34729938
http://dx.doi.org/10.1111/1759-7714.14184

Ejemplares similares