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A Novel Microcrystalline BAY-876 Formulation Achieves Long-Acting Antitumor Activity Against Aerobic Glycolysis and Proliferation of Hepatocellular Carcinoma

BAY-876 is an effective antagonist of the Glucose transporter type 1 (GLUT1) receptor, a mediator of aerobic glycolysis, a biological process considered a hallmark of hepatocellular carcinoma (HCC) together with cell proliferation, drug-resistance, and metastasis. However, the clinical application o...

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Detalles Bibliográficos
Autores principales: Yang, Hua, Zhang, Mu-Zi-he, Sun, Hui-wei, Chai, Yan-tao, Li, Xiaojuan, Jiang, Qiyu, Hou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636331/
https://www.ncbi.nlm.nih.gov/pubmed/34869036
http://dx.doi.org/10.3389/fonc.2021.783194