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A Novel Microcrystalline BAY-876 Formulation Achieves Long-Acting Antitumor Activity Against Aerobic Glycolysis and Proliferation of Hepatocellular Carcinoma
BAY-876 is an effective antagonist of the Glucose transporter type 1 (GLUT1) receptor, a mediator of aerobic glycolysis, a biological process considered a hallmark of hepatocellular carcinoma (HCC) together with cell proliferation, drug-resistance, and metastasis. However, the clinical application o...
Autores principales: | Yang, Hua, Zhang, Mu-Zi-he, Sun, Hui-wei, Chai, Yan-tao, Li, Xiaojuan, Jiang, Qiyu, Hou, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636331/ https://www.ncbi.nlm.nih.gov/pubmed/34869036 http://dx.doi.org/10.3389/fonc.2021.783194 |
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