GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity

The prevalence of non-obese nonalcoholic fatty liver disease (NAFLD) is increasing worldwide with unclear etiology and pathogenesis. Here, we show GP73, a Golgi protein upregulated in livers from patients with a variety of liver diseases, exhibits Rab GTPase-activating protein (GAP) activity regulat...

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Detalles Bibliográficos
Autores principales: Peng, Yumeng, Zeng, Qiang, Wan, Luming, Ma, Enhao, Li, Huilong, Yang, Xiaopan, Zhang, Yanhong, Huang, Linfei, Lin, Haotian, Feng, Jiangyue, Xu, Yixin, Li, Jingfei, Liu, Muyi, Liu, Jing, Lin, Changqin, Sun, Zhiwei, Cheng, Gong, Zhang, Xuemiao, Liu, Jialong, Li, Dongrui, Wei, Meng, Mo, Yunhai, Mu, Xuetao, Deng, Xiaowei, Zhang, Dandan, Dong, Siqing, Huang, Hanqing, Fang, Yi, Gao, Qi, Yang, Xiaoli, Wu, Feixiang, Zhong, Hui, Wei, Congwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636488/
https://www.ncbi.nlm.nih.gov/pubmed/34853313
http://dx.doi.org/10.1038/s41467-021-27309-1

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