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DNA repair inhibitors sensitize cells differently to high and low LET radiation

The aim of this study was to investigate effects of high LET α-radiation in combination with inhibitors of DDR (DNA-PK and ATM) and to compare the effect with the radiosensitizing effect of low LET X-ray radiation. The various cell lines were irradiated with α-radiation and with X-ray. Clonogenic su...

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Detalles Bibliográficos
Autores principales: Bannik, Kristina, Madas, Balázs, Jarke, Sabrina, Sutter, Andreas, Siemeister, Gerhard, Schatz, Christoph, Mumberg, Dominik, Zitzmann-Kolbe, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636489/
https://www.ncbi.nlm.nih.gov/pubmed/34853427
http://dx.doi.org/10.1038/s41598-021-02719-9