Cargando…

Native glycan fragments detected by MALDI mass spectrometry imaging are independent prognostic factors in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest malignancies to date. The impressively developed stroma that surrounds and modulates the behavior of cancer cells is one of the main factors regulating the PDAC growth, metastasis and therapy resistance. Here, we postul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Na, Trajkovic-Arsic, Marija, Li, Fengxia, Wu, Yin, Münch, Corinna, Kunzke, Thomas, Feuchtinger, Annette, Steiger, Katja, Schlitter, Anna Melissa, Weichert, Wilko, Esposito, Irene, Siveke, Jens T., Walch, Axel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636555/ https://www.ncbi.nlm.nih.gov/pubmed/34851463 http://dx.doi.org/10.1186/s13550-021-00862-y

Ejemplares similares

Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome
por: Kunzke, Thomas, et al.
Publicado: (2017)

MALDI-MSI: A Powerful Approach to Understand Primary Pancreatic Ductal Adenocarcinoma and Metastases
por: Gonçalves, Juliana Pereira Lopes, et al.
Publicado: (2022)

MALDI Mass Spectrometry Imaging—Prognostic Pathways and Metabolites for Renal Cell Carcinomas
por: Erlmeier, Franziska, et al.
Publicado: (2022)

MALDI Imaging Mass Spectrometry for In Situ Proteomic Analysis of Preneoplastic Lesions in Pancreatic Cancer
por: Grüner, Barbara M., et al.
Publicado: (2012)

X-Ray Phase-Contrast CT of a Pancreatic Ductal Adenocarcinoma Mouse Model
por: Tapfer, Arne, et al.
Publicado: (2013)

Apparent Diffusion Coefficient (ADC) predicts therapy response in pancreatic ductal adenocarcinoma
por: Trajkovic-Arsic, M., et al.
Publicado: (2017)

Perspective of α(v)β(6)-Integrin Imaging for Clinical Management of Pancreatic Carcinoma and Its Precursor Lesions
por: Steiger, Katja, et al.
Publicado: (2017)

Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma
por: Heid, Irina, et al.
Publicado: (2022)

A simple preparation step to remove excess liquid lipids in white adipose tissue enabling improved detection of metabolites via MALDI-FTICR imaging MS
por: Wang, Qian, et al.
Publicado: (2022)

The limits of molecular signatures for pancreatic ductal adenocarcinoma subtyping
por: Lautizi, Manuela, et al.
Publicado: (2022)

Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene
por: Schmohl, Kathrin A., et al.
Publicado: (2017)

A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy
por: Kaissis, Georgios, et al.
Publicado: (2019)

Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples
por: Blutke, Andreas, et al.
Publicado: (2020)

Image-Based Molecular Phenotyping of Pancreatic Ductal Adenocarcinoma
por: Kaissis, Georgios A., et al.
Publicado: (2020)

Multiparametric Modelling of Survival in Pancreatic Ductal Adenocarcinoma Using Clinical, Histomorphological, Genetic and Image-Derived Parameters
por: Kaissis, Georgios A., et al.
Publicado: (2020)

Functional biomarkers derived from computed tomography and magnetic resonance imaging differentiate PDAC subgroups and reveal gemcitabine-induced hypo-vascularization
por: Heid, Irina, et al.
Publicado: (2022)

Still a hopeless case for personalized oncology? Pancreatic cancer revisited
por: Weichert, Wilko, et al.
Publicado: (2018)

Is metabolism the magic bullet for targeted cancer therapy?
por: Trajkovic-Arsic, Marija, et al.
Publicado: (2023)

An analysis of 130 neuroendocrine tumors G3 regarding prevalence, origin, metastasis, and diagnostic features
por: Kasajima, Atsuko, et al.
Publicado: (2021)

MALDI Mass Spectrometry Imaging for the Distinction of Adenocarcinomas of the Pancreas and Biliary Tree
por: Bollwein, Christine, et al.
Publicado: (2022)

Fibroblast Activation Protein-Targeted Photodynamic Therapy of Cancer-Associated Fibroblasts in Murine Models for Pancreatic Ductal Adenocarcinoma
por: Dorst, Daphne N., et al.
Publicado: (2023)

A machine learning model for the prediction of survival and tumor subtype in pancreatic ductal adenocarcinoma from preoperative diffusion-weighted imaging
por: Kaissis, Georgios, et al.
Publicado: (2019)

De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry
por: Prade, Verena M., et al.
Publicado: (2020)

[(18)F]FDG PET/MRI enables early chemotherapy response prediction in pancreatic ductal adenocarcinoma
por: Harder, Felix N., et al.
Publicado: (2021)

Spatial metabolomics identifies distinct tumor-specific and stroma-specific subtypes in patients with lung squamous cell carcinoma
por: Wang, Jun, et al.
Publicado: (2023)

Loss of CDX2 in colorectal cancer is associated with histopathologic subtypes and microsatellite instability but is prognostically inferior to hematoxylin–eosin-based morphologic parameters from the WHO classification
por: Konukiewitz, Björn, et al.
Publicado: (2021)

Mesenchymal/non-epithelial mimickers of neuroendocrine neoplasms with a focus on fusion gene-associated and SWI/SNF-deficient tumors
por: Kasajima, Atsuko, et al.
Publicado: (2021)

MALDI-2 for the Enhanced Analysis of N-Linked Glycans by Mass Spectrometry Imaging
por: Heijs, Bram, et al.
Publicado: (2020)

MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo
por: Walter, Karolin, et al.
Publicado: (2019)

Molecular, morphological and survival analysis of 177 resected pancreatic ductal adenocarcinomas (PDACs): Identification of prognostic subtypes
por: Schlitter, Anna Melissa, et al.
Publicado: (2017)

Post-neoadjuvant cellular dissociation grading based on tumour budding and cell nest size is associated with therapy response and survival in oesophageal squamous cell carcinoma
por: Jesinghaus, Moritz, et al.
Publicado: (2019)

Dual Modifications Strategy to Quantify Neutral and Sialylated N-Glycans Simultaneously by MALDI-MS
por: Zhou, Hui, et al.
Publicado: (2014)

Comprehensive N-Glycan Profiling of Cetuximab Biosimilar Candidate by NP-HPLC and MALDI-MS
por: Liu, Sheng, et al.
Publicado: (2017)

Characterization of glycan isomers using magnetic carbon nanoparticles as a MALDI co-matrix
por: Banazadeh, Alireza, et al.
Publicado: (2019)

Device-Controlled Microcondensation for Spatially Confined On-Tissue Digests in MALDI Imaging of N-Glycans
por: Fülöp, Annabelle, et al.
Publicado: (2022)

Glycan fragment database: a database of PDB-based glycan 3D structures
por: Jo, Sunhwan, et al.
Publicado: (2013)

Whole Exome Sequencing of Biliary Tubulopapillary Neoplasms Reveals Common Mutations in Chromatin Remodeling Genes
por: Gross, Claudia, et al.
Publicado: (2021)

The Impact of Histological Annotations for Accurate Tissue Classification Using Mass Spectrometry Imaging
por: Gonçalves, Juliana Pereira Lopes, et al.
Publicado: (2021)

Hyperpolarized (13)C pyruvate magnetic resonance spectroscopy for in vivo metabolic phenotyping of rat HCC
por: Bliemsrieder, Elisabeth, et al.
Publicado: (2021)

Author Correction: Hyperpolarized (13)C pyruvate magnetic resonance spectroscopy for in vivo metabolic phenotyping of rat HCC
por: Bliemsrieder, Elisabeth, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4nesiidbv84bv388m7s7ij8d65