Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation

Defects in chromosome-microtubule attachment can cause chromosomal instability (CIN), frequently associated with infertility and aggressive cancers. Chromosome-microtubule attachment is mediated by a large macromolecular structure, the kinetochore. Sister kinetochores of each chromosome are pulled b...

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Detalles Bibliográficos
Autores principales: Song, Xinhong, Conti, Duccio, Shrestha, Roshan L., Braun, Dominique, Draviam, Viji M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636589/
https://www.ncbi.nlm.nih.gov/pubmed/34853300
http://dx.doi.org/10.1038/s41467-021-27131-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636589/
https://www.ncbi.nlm.nih.gov/pubmed/34853300
http://dx.doi.org/10.1038/s41467-021-27131-9

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