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Age-related exacerbation of hematopoietic organ damage induced by systemic hyper-inflammation in senescence-accelerated mice

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening systemic hyper-inflammatory disorder. The mortality of HLH is higher in the elderly than in young adults. Senescence-accelerated mice (SAMP1/TA-1) exhibit characteristic accelerated aging after 30 weeks of age, and HLH-like features, inc...

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Detalles Bibliográficos
Autores principales:	Harada, Tomonori, Tsuboi, Isao, Hino, Hirotsugu, Yuda, Miyuki, Hirabayashi, Yoko, Hirai, Shuichi, Aizawa, Shin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636590/ https://www.ncbi.nlm.nih.gov/pubmed/34853370 http://dx.doi.org/10.1038/s41598-021-02621-4

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