Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids

Inhibition of RTK pathways in cancer triggers an adaptive response that promotes therapeutic resistance. Because the adaptive response is multifaceted, the optimal approach to blunting it remains undetermined. TNF upregulation is a biologically significant response to EGFR inhibition in NSCLC. Here,...

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Detalles Bibliográficos
Autores principales: Gong, Ke, Guo, Gao, Beckley, Nicole A., Yang, Xiaoyao, Zhang, Yue, Gerber, David E., Minna, John D., Burma, Sandeep, Zhao, Dawen, Akbay, Esra A., Habib, Amyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636603/
https://www.ncbi.nlm.nih.gov/pubmed/34853306
http://dx.doi.org/10.1038/s41467-021-27276-7

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