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Pan-cancer analysis of non-oncogene addiction to DNA repair
Cancer cells usually depend on the aberrant function of one or few driver genes to initiate and promote their malignancy, an attribute known as oncogene addiction. However, cancer cells might become dependent on the normal cellular functions of certain genes that are not oncogenes but ensure cell su...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636604/ https://www.ncbi.nlm.nih.gov/pubmed/34853396 http://dx.doi.org/10.1038/s41598-021-02773-3 |