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Pan-cancer analysis of non-oncogene addiction to DNA repair

Cancer cells usually depend on the aberrant function of one or few driver genes to initiate and promote their malignancy, an attribute known as oncogene addiction. However, cancer cells might become dependent on the normal cellular functions of certain genes that are not oncogenes but ensure cell su...

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Detalles Bibliográficos
Autor principal: Bermúdez-Guzmán, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636604/
https://www.ncbi.nlm.nih.gov/pubmed/34853396
http://dx.doi.org/10.1038/s41598-021-02773-3