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Mechanism of Rad26-assisted rescue of stalled RNA polymerase II in transcription-coupled repair

Transcription-coupled repair is essential for the removal of DNA lesions from the transcribed genome. The pathway is initiated by CSB protein binding to stalled RNA polymerase II. Mutations impairing CSB function cause severe genetic disease. Yet, the ATP-dependent mechanism by which CSB powers RNA...

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Detalles Bibliográficos
Autores principales:	Yan, Chunli, Dodd, Thomas, Yu, Jina, Leung, Bernice, Xu, Jun, Oh, Juntaek, Wang, Dong, Ivanov, Ivaylo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636621/ https://www.ncbi.nlm.nih.gov/pubmed/34853308 http://dx.doi.org/10.1038/s41467-021-27295-4

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