Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of human esophageal cancer

Nicotine addiction and the occurrence of lymph node spread are two major significant factors associated with esophageal cancer’s poor prognosis; however, nicotine’s role in inducing lymphatic metastasis of esophageal cancer remains unclear. Here we show that OTU domain-containing protein 3 (OTUD3) i...

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Detalles Bibliográficos
Autores principales: Wang, Meng, Li, Yue, Xiao, Yunyun, Yang, Muwen, Chen, Jinxin, Jian, Yunting, Chen, Xin, Shi, Dongni, Chen, Xiangfu, Ouyang, Ying, Kong, Lingzhi, Huang, Xinjian, Bai, Jiewen, Lin, Chuyong, Song, Libing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636640/
https://www.ncbi.nlm.nih.gov/pubmed/34853315
http://dx.doi.org/10.1038/s41467-021-27348-8

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