A novel RNA-mediated mechanism causing down-regulation of insulating promoter interactions in human embryonic stem cells

The genome-wide promoter interactome is primarily maintained and regulated by architectural proteins such as CTCF and cohesin. However, some studies suggest a role for non-coding RNAs (ncRNAs) in this process. We aimed to characterise the regulatory role of RNA-mediated promoter interactions in the...

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Detalles Bibliográficos
Autores principales: Liu, Yingjuan, Williams, Simon G., Jones, Hayden R., Keavney, Bernard D., Choy, Mun-Kit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636647/
https://www.ncbi.nlm.nih.gov/pubmed/34853328
http://dx.doi.org/10.1038/s41598-021-02373-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636647/
https://www.ncbi.nlm.nih.gov/pubmed/34853328
http://dx.doi.org/10.1038/s41598-021-02373-1

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