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A novel RNA-mediated mechanism causing down-regulation of insulating promoter interactions in human embryonic stem cells
The genome-wide promoter interactome is primarily maintained and regulated by architectural proteins such as CTCF and cohesin. However, some studies suggest a role for non-coding RNAs (ncRNAs) in this process. We aimed to characterise the regulatory role of RNA-mediated promoter interactions in the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636647/ https://www.ncbi.nlm.nih.gov/pubmed/34853328 http://dx.doi.org/10.1038/s41598-021-02373-1 |