3D collagen matrices modulate the transcriptional trajectory of bone marrow hematopoietic progenitors into macrophage lineage commitment

Physical signals provided by the extracellular matrix (ECM) are key microenvironmental parameters for the fate decision of hematopoietic stem and progenitor cells (HSPC) in bone marrow. Insights into cell-ECM interactions are critical for advancing HSC-based tissue engineering. Herein, we employed c...

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Detalles Bibliográficos
Autores principales: Zhang, Pan, Xu, Linmu, Gao, Jingsong, Xu, Guangkui, Song, Yanping, Li, Guang, Ren, Jingjing, Zhang, Yunjie, Yang, Cheng, Zhang, Yu, Xie, Ruiheng, Zhang, Nu, Yang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636680/
https://www.ncbi.nlm.nih.gov/pubmed/34901544
http://dx.doi.org/10.1016/j.bioactmat.2021.08.032

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