Cargando…

24-Hour Profiles of 11-Oxygenated C(19) Steroids and Δ(5)-Steroid Sulfates during Oral and Continuous Subcutaneous Glucocorticoids in 21-Hydroxylase Deficiency

BACKGROUND: Optimal management of androgen excess in 21-hydroxylase deficiency (21OHD) remains challenging. 11-oxygenated-C(19) steroids (11-oxyandrogens) have emerged as promising biomarkers of disease control, but data regarding their response to treatment are lacking. OBJECTIVE: To compare the dy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Turcu, Adina F., Mallappa, Ashwini, Nella, Aikaterini A., Chen, Xuan, Zhao, Lili, Nanba, Aya T., Byrd, James Brian, Auchus, Richard J., Merke, Deborah P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636728/ https://www.ncbi.nlm.nih.gov/pubmed/34867794 http://dx.doi.org/10.3389/fendo.2021.751191

Ejemplares similares

SUN-360 Multi-Steroid Panels to Replace Dynamic Testing for the Diagnosis of Nonclassic 21-Hydroxylase Deficiency
por: Turcu, Adina, et al.
Publicado: (2019)

11-Oxygenated Androgens Are Biomarkers of Adrenal Volume and Testicular Adrenal Rest Tumors in 21-Hydroxylase Deficiency
por: Turcu, Adina F., et al.
Publicado: (2017)

Interpretation of Steroid Biomarkers in 21-Hydroxylase Deficiency and Their Use in Disease Management
por: Sarafoglou, Kyriakie, et al.
Publicado: (2023)

SUN-037 Discordant Serum 17-hydroxyprogesterone and Androstenedione in the Management of Congenital Adrenal Hyperplasia: Are 11-oxygenated Androgens Useful?
por: Jha, Smita, et al.
Publicado: (2020)

SAT-067 Insights into Paradoxical Bilateral Aldosterone Suppression in the Adrenal Veins of Patients with Primary Aldosteronism
por: Wannachalee, Taweesak, et al.
Publicado: (2019)

SUN-364 In Search of Predictors of Concordance between Imaging and Adrenal Vein Sampling in Unilateral Primary Aldosteronism
por: Wannachalee, Taweesak, et al.
Publicado: (2019)

SAT-061 Determinants of Cosyntropin Effect on Adrenal Vein Sampling Lateralization in Primary Aldosteronism
por: Wannachalee, Taweesak, et al.
Publicado: (2019)

Steroid Sulfation in Neurodegenerative Diseases
por: Vitku, Jana, et al.
Publicado: (2022)

Prenatal Diagnosis and Treatment of Steroid 21-Hydroxylase Deficiency
por: Tajima, Toshihiro, et al.
Publicado: (2008)

Alterations in Hydrocortisone Pharmacokinetics in a Patient With Congenital Adrenal Hyperplasia Following Bariatric Surgery
por: Mallappa, Ashwini, et al.
Publicado: (2017)

RF10 | PMON221 11-Oxygenated-Androgens in Females with Severe Insulin Resistance
por: Merke, Deborah, et al.
Publicado: (2022)

Management challenges and therapeutic advances in congenital adrenal hyperplasia
por: Mallappa, Ashwini, et al.
Publicado: (2022)

The Regulation of Steroid Action by Sulfation and Desulfation
por: Mueller, Jonathan W., et al.
Publicado: (2015)

Steroid 21-hydroxylase gene variants and late-life depression
por: Ancelin, Marie-Laure, et al.
Publicado: (2021)

A Summary of the Endocrine Society Clinical Practice Guidelines on Congenital Adrenal Hyperplasia due to Steroid 21-Hydroxylase Deficiency
por: Speiser, Phyllis W., et al.
Publicado: (2010)

MON-183 Adrenal Androgen Control and Steroidal Side Effects in Adolescents and Adults with Congenital Adrenal Hyperplasia Treated with Glucocorticoids
por: Falhammar, Henrik, et al.
Publicado: (2020)

Bacterial steroid hydroxylases: enzyme classes, their functions and comparison of their catalytic mechanisms
por: Szaleniec, Maciej, et al.
Publicado: (2018)

Corticosteroid Biosynthesis Revisited: No Direct Hydroxylation of Pregnenolone by Steroid 21-Hydroxylase
por: Loke, Steffen, et al.
Publicado: (2021)

Molecular Diagnosis of Steroid 21-Hydroxylase Deficiency: A Practical Approach
por: Arriba, María, et al.
Publicado: (2022)

Sulfated and Sulfur-Containing Steroids and Their Pharmacological Profile
por: Pounina, Tatyana A., et al.
Publicado: (2021)

Duration of Suppression of Adrenal Steroids after Glucocorticoid Administration
por: Fuqua, John S., et al.
Publicado: (2010)

Sex steroids and glucocorticoid ratios in Iberian lynx hair
por: Azevedo, Alexandre, et al.
Publicado: (2020)

Mechanisms and Clinical Applications of Glucocorticoid Steroids in Muscular Dystrophy
por: Quattrocelli, Mattia, et al.
Publicado: (2021)

Contribution of local regeneration of glucocorticoids to tissue steroid pools
por: Khan, S, et al.
Publicado: (2022)

SAT-010 Adrenal Androgen Synthesis in Aging Men
por: Namba, Aya, et al.
Publicado: (2019)

Hydroxylation and sulfation of sex steroid hormones in inflammatory liver
por: Lee, Sang R., et al.
Publicado: (2017)

Exogenous Testosterone Does Not Influence 11-Oxygenated C19 Steroid Concentrations in Healthy Postmenopausal Women
por: Davis, Susan R, et al.
Publicado: (2019)

The Impact of ACTH on Peripheral Steroids Differs between Unilateral and Bilateral Primary Aldosteronism
por: Tezuka, Yuta, et al.
Publicado: (2021)

Structural analysis of the evolution of steroid specificity in the mineralocorticoid and glucocorticoid receptors
por: Baker, Michael E, et al.
Publicado: (2007)

Expression of Key Androgen-Activating Enzymes in Ovarian Steroid Cell Tumor, Not Otherwise Specified
por: Valenzuela Scheker, Evana, et al.
Publicado: (2020)

Four Molybdenum-Dependent Steroid C-25 Hydroxylases: Heterologous Overproduction, Role in Steroid Degradation, and Application for 25-Hydroxyvitamin D(3) Synthesis
por: Jacoby, Christian, et al.
Publicado: (2018)

SUN-LB4 Androgenic Profiles of Patients With Severe Insulin Resistance
por: Jha, Smita, et al.
Publicado: (2020)

Flow cytometry analysis of glucocorticoid receptor expression and binding in steroid-sensitive and steroid-resistant patients with systemic lupus erythematosus
por: Du, Juan, et al.
Publicado: (2009)

Assay of steroids by liquid chromatography–tandem mass spectrometry in monitoring 21-hydroxylase deficiency
por: Dahl, Sandra R, et al.
Publicado: (2018)

Identification and expression of the 11β‐steroid hydroxylase from Cochliobolus lunatus in Corynebacterium glutamicum
por: Felpeto‐Santero, Carmen, et al.
Publicado: (2019)

Clinical Trial of Subcutaneous Steroid Injection in Patients with Migraine Disorder
por: Nikkhah, Karim, et al.
Publicado: (2016)

Dual processing of sulfated steroids in the olfactory system of an anuran amphibian
por: Sansone, Alfredo, et al.
Publicado: (2015)

Pregnenolone Sulfate: From Steroid Metabolite to TRP Channel Ligand
por: Harteneck, Christian
Publicado: (2013)

Role of Chondroitin Sulfate Proteoglycan 5 in Steroid-Induced Cataract
por: Yoo, Woong-Sun, et al.
Publicado: (2023)

Congenital Adrenal Hyperplasia Presenting as an Adrenal Mass With Increased (18)F-FDG Positron Emission Tomography Uptake
por: Mallappa, Ashwini, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_tq7iued8r1in0vk19qraspfvm9