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A bone-targeted engineered exosome platform delivering siRNA to treat osteoporosis
The complex pathogenesis of osteoporosis includes excessive bone resorption, insufficient bone formation and inadequate vascularization, a combination which is difficult to completely address with conventional therapies. Engineered exosomes carrying curative molecules show promise as alternative ost...
Autores principales: | Cui, Yongzhi, Guo, Yuanyuan, Kong, Li, Shi, Jingyu, Liu, Ping, Li, Rui, Geng, Yongtao, Gao, Weihang, Zhang, Zhiping, Fu, Dehao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636739/ https://www.ncbi.nlm.nih.gov/pubmed/34901540 http://dx.doi.org/10.1016/j.bioactmat.2021.09.015 |
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