Cargando…

TRAIL sensitivity of nasopharyngeal cancer cells involves redox dependent upregulation of TMTC2 and its interaction with membrane caspase-3

AIMS: Preferential expression of receptors for TNF-family related apoptosis inducing ligand (TRAIL), DR4 and DR5 makes TRAIL an attractive anti-cancer therapeutic. However, the efficacy of targeting death receptors has not been extensively studied in nasopharyngeal cancer (NPC). Here we investigated...

Descripción completa

Detalles Bibliográficos
Autores principales: Raman, Deepika, Tay, Patricia, Hirpara, Jayshree L., Liu, Dan, Pervaiz, Shazib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636823/
https://www.ncbi.nlm.nih.gov/pubmed/34839142
http://dx.doi.org/10.1016/j.redox.2021.102193