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Polyclonal Regulatory T Cell Manufacturing Under cGMP: A Decade of Experience

We report on manufacturing outcomes for 41 autologous polyclonal regulatory T cell (PolyTreg) products for 7 different Phase 1 clinical trials over a 10-year period (2011-2020). Data on patient characteristics, manufacturing parameters, and manufacturing outcomes were collected from manufacturing ba...

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Detalles Bibliográficos
Autores principales:	Balcerek, Joanna, Shy, Brian R., Putnam, Amy L., Masiello, Lisa M., Lares, Angela, Dekovic, Florinna, Acevedo, Luis, Lee, Michael R., Nguyen, Vinh, Liu, Weihong, Paruthiyil, Sreenivasan, Xu, Jingying, Leinbach, Ashley S., Bluestone, Jeffrey A., Tang, Qizhi, Esensten, Jonathan H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636860/ https://www.ncbi.nlm.nih.gov/pubmed/34867967 http://dx.doi.org/10.3389/fimmu.2021.744763

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