Seroprevalence of antibodies against severe acute respiratory coronavirus 2 (SARS-CoV-2) in household dogs in Japan

We investigated the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among dogs in the Tokyo area via enzyme-linked immunosorbent assay (ELISA) using the spike protein as the target antigen. Plasma samples from 494 household dogs and blood-donor dogs were tested from Ju...

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Autores principales: ITO, Genta, GOTO-KOSHINO, Yuko, KURODA, Yudai, EUNSIL, Park, MAEDA, Ken, SOMA, Takehisa, MOMOI, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636879/
https://www.ncbi.nlm.nih.gov/pubmed/34556605
http://dx.doi.org/10.1292/jvms.21-0338
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author ITO, Genta
GOTO-KOSHINO, Yuko
KURODA, Yudai
EUNSIL, Park
MAEDA, Ken
SOMA, Takehisa
MOMOI, Yasuyuki
author_facet ITO, Genta
GOTO-KOSHINO, Yuko
KURODA, Yudai
EUNSIL, Park
MAEDA, Ken
SOMA, Takehisa
MOMOI, Yasuyuki
author_sort ITO, Genta
collection PubMed
description We investigated the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among dogs in the Tokyo area via enzyme-linked immunosorbent assay (ELISA) using the spike protein as the target antigen. Plasma samples from 494 household dogs and blood-donor dogs were tested from July 2020 to January 2021. Of these samples, three showed optical densities that were higher than the mean plus two standard deviations of the mean of the negative-control optical densities (ODs). Of these three samples, only the sample with the highest OD by ELISA was confirmed positive by virus neutralization testing. The positive dog presented no SARS-CoV-2-related symptoms. The positivity rate of SARS-CoV-2 infections among dogs in the Tokyo area was approximately 0.2%.
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spelling pubmed-86368792021-12-07 Seroprevalence of antibodies against severe acute respiratory coronavirus 2 (SARS-CoV-2) in household dogs in Japan ITO, Genta GOTO-KOSHINO, Yuko KURODA, Yudai EUNSIL, Park MAEDA, Ken SOMA, Takehisa MOMOI, Yasuyuki J Vet Med Sci Internal Medicine We investigated the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among dogs in the Tokyo area via enzyme-linked immunosorbent assay (ELISA) using the spike protein as the target antigen. Plasma samples from 494 household dogs and blood-donor dogs were tested from July 2020 to January 2021. Of these samples, three showed optical densities that were higher than the mean plus two standard deviations of the mean of the negative-control optical densities (ODs). Of these three samples, only the sample with the highest OD by ELISA was confirmed positive by virus neutralization testing. The positive dog presented no SARS-CoV-2-related symptoms. The positivity rate of SARS-CoV-2 infections among dogs in the Tokyo area was approximately 0.2%. The Japanese Society of Veterinary Science 2021-09-24 2021-11 /pmc/articles/PMC8636879/ /pubmed/34556605 http://dx.doi.org/10.1292/jvms.21-0338 Text en ©2021 The Japanese Society of Veterinary Science https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Internal Medicine
ITO, Genta
GOTO-KOSHINO, Yuko
KURODA, Yudai
EUNSIL, Park
MAEDA, Ken
SOMA, Takehisa
MOMOI, Yasuyuki
Seroprevalence of antibodies against severe acute respiratory coronavirus 2 (SARS-CoV-2) in household dogs in Japan
title Seroprevalence of antibodies against severe acute respiratory coronavirus 2 (SARS-CoV-2) in household dogs in Japan
title_full Seroprevalence of antibodies against severe acute respiratory coronavirus 2 (SARS-CoV-2) in household dogs in Japan
title_fullStr Seroprevalence of antibodies against severe acute respiratory coronavirus 2 (SARS-CoV-2) in household dogs in Japan
title_full_unstemmed Seroprevalence of antibodies against severe acute respiratory coronavirus 2 (SARS-CoV-2) in household dogs in Japan
title_short Seroprevalence of antibodies against severe acute respiratory coronavirus 2 (SARS-CoV-2) in household dogs in Japan
title_sort seroprevalence of antibodies against severe acute respiratory coronavirus 2 (sars-cov-2) in household dogs in japan
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636879/
https://www.ncbi.nlm.nih.gov/pubmed/34556605
http://dx.doi.org/10.1292/jvms.21-0338
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