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Effects of Subtypes of Child Maltreatment on CRP in Adulthood

In order to evaluate the effects of specific forms of childhood maltreatment (CM) upon adult C-reactive protein (CRP) concentrations, and to further describe the potentially confounding role that recent life stress and depression hold in that relationship, 221 participants from rural Australia (M ag...

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Autores principales: Bitsika, Vicki, Sharpley, Christopher F., McMillan, Mary E., Jesulola, Emmanuel, Agnew, Linda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637154/
https://www.ncbi.nlm.nih.gov/pubmed/34867491
http://dx.doi.org/10.3389/fpsyt.2021.533722
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author Bitsika, Vicki
Sharpley, Christopher F.
McMillan, Mary E.
Jesulola, Emmanuel
Agnew, Linda L.
author_facet Bitsika, Vicki
Sharpley, Christopher F.
McMillan, Mary E.
Jesulola, Emmanuel
Agnew, Linda L.
author_sort Bitsika, Vicki
collection PubMed
description In order to evaluate the effects of specific forms of childhood maltreatment (CM) upon adult C-reactive protein (CRP) concentrations, and to further describe the potentially confounding role that recent life stress and depression hold in that relationship, 221 participants from rural Australia (M age = 44yr, SD = 17.8yr) completed self-report questionnaires and provided a blood sample. There were no sex differences in any variables across the 91 males and 130 females, but depression status did confound the association between global CM and CRP. The specific aspect of CM was identified as physical and mental health abuse, and this was significantly associated with CRP level in participants with depressive symptoms and those without. There was no significant confound from recent life stressors. Results hold implications for the diagnosis of CM-related CRP elevation and (potentially) depression.
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spelling pubmed-86371542021-12-03 Effects of Subtypes of Child Maltreatment on CRP in Adulthood Bitsika, Vicki Sharpley, Christopher F. McMillan, Mary E. Jesulola, Emmanuel Agnew, Linda L. Front Psychiatry Psychiatry In order to evaluate the effects of specific forms of childhood maltreatment (CM) upon adult C-reactive protein (CRP) concentrations, and to further describe the potentially confounding role that recent life stress and depression hold in that relationship, 221 participants from rural Australia (M age = 44yr, SD = 17.8yr) completed self-report questionnaires and provided a blood sample. There were no sex differences in any variables across the 91 males and 130 females, but depression status did confound the association between global CM and CRP. The specific aspect of CM was identified as physical and mental health abuse, and this was significantly associated with CRP level in participants with depressive symptoms and those without. There was no significant confound from recent life stressors. Results hold implications for the diagnosis of CM-related CRP elevation and (potentially) depression. Frontiers Media S.A. 2021-11-18 /pmc/articles/PMC8637154/ /pubmed/34867491 http://dx.doi.org/10.3389/fpsyt.2021.533722 Text en Copyright © 2021 Bitsika, Sharpley, McMillan, Jesulola and Agnew. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Bitsika, Vicki
Sharpley, Christopher F.
McMillan, Mary E.
Jesulola, Emmanuel
Agnew, Linda L.
Effects of Subtypes of Child Maltreatment on CRP in Adulthood
title Effects of Subtypes of Child Maltreatment on CRP in Adulthood
title_full Effects of Subtypes of Child Maltreatment on CRP in Adulthood
title_fullStr Effects of Subtypes of Child Maltreatment on CRP in Adulthood
title_full_unstemmed Effects of Subtypes of Child Maltreatment on CRP in Adulthood
title_short Effects of Subtypes of Child Maltreatment on CRP in Adulthood
title_sort effects of subtypes of child maltreatment on crp in adulthood
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637154/
https://www.ncbi.nlm.nih.gov/pubmed/34867491
http://dx.doi.org/10.3389/fpsyt.2021.533722
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