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Leukotriene D(4) Upregulates Oxidized Low-Density Lipoprotein Receptor 1 and CD36 to Enhance Oxidized LDL Uptake and Phagocytosis in Macrophages Through Cysteinyl Leukotriene Receptor 1
Endothelial permeability, leukocyte attachment, and unregulated oxidized LDL (oxLDL) uptake by macrophages leading to the formation of foam cells are all vital in the initiation and progression of atherosclerosis. During inflammation, several inflammatory mediators regulate this process through the...
Autores principales: | Pokhrel, Sabita, Gudneppanavar, Ravindra, Teegala, Lakshminarayan Reddy, Duah, Ernest, Thodeti, Charles K., Paruchuri, Sailaja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637273/ https://www.ncbi.nlm.nih.gov/pubmed/34867460 http://dx.doi.org/10.3389/fphys.2021.756450 |
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