T-Cell Epitopes Shared Between Immunizing HLA and Donor HLA Associate With Graft Failure After Kidney Transplantation

CD4(+) T-helper cells play an important role in alloimmune reactions following transplantation by stimulating humoral as well as cellular responses, which might lead to failure of the allograft. CD4(+) memory T-helper cells from a previous immunizing event can potentially be reactivated by exposure...

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Detalles Bibliográficos
Autores principales: Peereboom, Emma T. M., Matern, Benedict M., Tomosugi, Toshihide, Niemann, Matthias, Drylewicz, Julia, Joosten, Irma, Allebes, Wil A., van der Meer, Arnold, Hilbrands, Luuk B., Baas, Marije C., van Reekum, Franka E., Verhaar, Marianne C., Kamburova, Elena G., Seelen, Marc A. J., Sanders, Jan Stephan, Hepkema, Bouke G., Lambeck, Annechien J., Bungener, Laura B., Roozendaal, Caroline, Tilanus, Marcel G. J., Voorter, Christien E., Wieten, Lotte, van Duijnhoven, Elly M., Gelens, Mariëlle A. C. J., Christiaans, Maarten H. L., van Ittersum, Frans J., Nurmohamed, Azam, Lardy, Neubury M., Swelsen, Wendy, van der Pant, Karlijn A., van der Weerd, Neelke C., ten Berge, Ineke J. M., Bemelman, Fréderike J., de Vries, Aiko P. J., de Fijter, Johan W., Betjes, Michiel G. H., Roelen, Dave L., Claas, Frans H., Otten, Henny G., Heidt, Sebastiaan, van Zuilen, Arjan D., Kobayashi, Takaaki, Geneugelijk, Kirsten, Spierings, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637278/
https://www.ncbi.nlm.nih.gov/pubmed/34868064
http://dx.doi.org/10.3389/fimmu.2021.784040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637278/
https://www.ncbi.nlm.nih.gov/pubmed/34868064
http://dx.doi.org/10.3389/fimmu.2021.784040

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