Cargando…

Modulation of Cystatin C in Human Macrophages Improves Anti-Mycobacterial Immune Responses to Mycobacterium tuberculosis Infection and Coinfection With HIV

Tuberculosis owes its resurgence as a major global health threat mostly to the emergence of drug resistance and coinfection with HIV. The synergy between HIV and Mycobacterium tuberculosis (Mtb) modifies the host immune environment to enhance both viral and bacterial replication and spread. In the l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pires, David, Calado, Marta, Velez, Tomás, Mandal, Manoj, Catalão, Maria João, Neyrolles, Olivier, Lugo-Villarino, Geanncarlo, Vérollet, Christel, Azevedo-Pereira, José Miguel, Anes, Elsa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637326/ https://www.ncbi.nlm.nih.gov/pubmed/34867965 http://dx.doi.org/10.3389/fimmu.2021.742822

Ejemplares similares

Macrophage Polarization: Convergence Point Targeted by Mycobacterium Tuberculosis and HIV
por: Lugo-Villarino, Geanncarlo, et al.
Publicado: (2011)

Modulation of Cystatin F in Human Macrophages Impacts Cathepsin-Driven Killing of Multidrug-Resistant Mycobacterium tuberculosis
por: Mandal, Manoj, et al.
Publicado: (2023)

Role of Cathepsins in Mycobacterium tuberculosis Survival in Human Macrophages
por: Pires, David, et al.
Publicado: (2016)

Development of Chitosan Particles Loaded with siRNA for Cystatin C to Control Intracellular Drug-Resistant Mycobacterium tuberculosis
por: Pires, David, et al.
Publicado: (2023)

Tunneling Nanotubes: Intimate Communication between Myeloid Cells
por: Dupont, Maeva, et al.
Publicado: (2018)

Repurposing Saquinavir for Host-Directed Therapy to Control Mycobacterium Tuberculosis Infection
por: Pires, David, et al.
Publicado: (2021)

Editorial: The Mononuclear Phagocyte System in Infectious Disease
por: Lugo-Villarino, Geanncarlo, et al.
Publicado: (2019)

Liposomal Delivery of Saquinavir to Macrophages Overcomes Cathepsin Blockade by Mycobacterium tuberculosis and Helps Control the Phagosomal Replicative Niches
por: Pires, David, et al.
Publicado: (2023)

ESAT-6 a Major Virulence Factor of Mycobacterium tuberculosis
por: Anes, Elsa, et al.
Publicado: (2023)

Actin-binding protein regulation by microRNAs as a novel microbial strategy to modulate phagocytosis by host cells: the case of N-Wasp and miR-142-3p
por: Bettencourt, Paulo, et al.
Publicado: (2013)

Emerging Trends in the Formation and Function of Tuberculosis Granulomas
por: Lugo-Villarino, Geanncarlo, et al.
Publicado: (2013)

Playing hide-and-seek with host macrophages through the use of mycobacterial cell envelope phthiocerol dimycocerosates and phenolic glycolipids
por: Arbues, Ainhoa, et al.
Publicado: (2014)

Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α activation
por: Genoula, Melanie, et al.
Publicado: (2020)

HIV/Mtb Co-Infection: From the Amplification of Disease Pathogenesis to an “Emerging Syndemic”
por: Azevedo-Pereira, José Miguel, et al.
Publicado: (2023)

CRISPRi-mediated characterization of novel anti-tuberculosis targets: Mycobacterial peptidoglycan modifications promote beta-lactam resistance and intracellular survival
por: Silveiro, Cátia, et al.
Publicado: (2023)

Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate
por: Gouzy, Alexandre, et al.
Publicado: (2013)

Mycobacterial P(1)-Type ATPases Mediate Resistance to Zinc Poisoning in Human Macrophages
por: Botella, Hélène, et al.
Publicado: (2011)

Cathepsins and Their Endogenous Inhibitors in Host Defense During Mycobacterium tuberculosis and HIV Infection
por: Anes, Elsa, et al.
Publicado: (2021)

Spatial localization of cathepsins: Implications in immune activation and resolution during infections
por: Anes, Elsa, et al.
Publicado: (2022)

Collectin CL-LK Is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis
por: Troegeler, Anthony, et al.
Publicado: (2015)

Uncovering Beta-Lactam Susceptibility Patterns in Clinical Isolates of Mycobacterium tuberculosis through Whole-Genome Sequencing
por: Olivença, Francisco, et al.
Publicado: (2022)

Podosomes, But Not the Maturation Status, Determine the Protease-Dependent 3D Migration in Human Dendritic Cells
por: Cougoule, Céline, et al.
Publicado: (2018)

The C-Type Lectin Receptor DC-SIGN Has an Anti-Inflammatory Role in Human M(IL-4) Macrophages in Response to Mycobacterium tuberculosis
por: Lugo-Villarino, Geanncarlo, et al.
Publicado: (2018)

Variability in the virulence of specific Mycobacterium tuberculosis clinical isolates alters the capacity of human dendritic cells to signal for T cells
por: Ramos-Martinez, Ana Gabriela, et al.
Publicado: (2019)

Type-2 diabetes alters the basal phenotype of human macrophages and diminishes their capacity to respond, internalise, and control Mycobacterium tuberculosis
por: Lopez-Lopez, Nallely, et al.
Publicado: (2018)

Cell-to-Cell Transmission of HIV-1 and HIV-2 from Infected Macrophages and Dendritic Cells to CD4+ T Lymphocytes
por: Calado, Marta, et al.
Publicado: (2023)

Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages
por: Dupont, Maeva, et al.
Publicado: (2020)

Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles
por: Benet, Susana, et al.
Publicado: (2021)

Mycobacteriophage Lysis Enzymes: Targeting the Mycobacterial Cell Envelope
por: Catalão, Maria João, et al.
Publicado: (2018)

A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection
por: Siddle, Katherine J., et al.
Publicado: (2014)

Fluoroquinolone Derivatives in the Treatment of Mycobacterium tuberculosis Infection
por: Pais, João Pedro, et al.
Publicado: (2022)

Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis
por: Machado, Diana, et al.
Publicado: (2016)

Formation of Foamy Macrophages by Tuberculous Pleural Effusions Is Triggered by the Interleukin-10/Signal Transducer and Activator of Transcription 3 Axis through ACAT Upregulation
por: Genoula, Melanie, et al.
Publicado: (2018)

Mycobacterium abscessus: Shapeshifter of the Mycobacterial World
por: Ryan, Keenan, et al.
Publicado: (2018)

The fat is in the lysosome: how Mycobacterium tuberculosis tricks macrophages into storing lipids
por: Rombouts, Yoann, et al.
Publicado: (2023)

Identification of drivers of mycobacterial resistance to peptidoglycan synthesis inhibitors
por: Olivença, Francisco, et al.
Publicado: (2022)

HIV-1 Infection of T Lymphocytes and Macrophages Affects Their Migration via Nef
por: Vérollet, Christel, et al.
Publicado: (2015)

COVID-19 and Pulmonary Mycobacterium Tuberculosis Coinfection
por: Al Lawati, Redha, et al.
Publicado: (2021)

Sphingosine Kinase-1 (SphK-1) Regulates Mycobacterium smegmatis Infection in Macrophages
por: Prakash, Hridayesh, et al.
Publicado: (2010)

Mycobacterial panniculitis caused by Mycobacterium thermoresistibile in a cat
por: Vishkautsan, Polina, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_gqoodvaorvo667pp3377i8g9ka