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Structural Modifications Yield Novel Insights Into the Intriguing Pharmacodynamic Potential of Anti-inflammatory Nitro-Fatty Acids

Endogenous nitro-fatty acids (NFA) are potent electrophilic lipid mediators that exert biological effects in vitro and in vivo via selective covalent modification of thiol-containing target proteins. The cytoprotective, anti-inflammatory, and anti-tumorigenic effects of NFA in animal models of disea...

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Detalles Bibliográficos
Autores principales: Hellmuth, Nadine, Brat, Camilla, Awad, Omar, George, Sven, Kahnt, Astrid, Bauer, Tom, Huynh Phuoc, Hai Phong, Steinhilber, Dieter, Angioni, Carlo, Hassan, Mohamed, Hock, Katharina J., Manolikakes, Georg, Zacharowski, Kai, Roos, Jessica, Maier, Thorsten J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637440/
https://www.ncbi.nlm.nih.gov/pubmed/34867322
http://dx.doi.org/10.3389/fphar.2021.715076