A DNA damage repair gene‐associated signature predicts responses of patients with advanced soft‐tissue sarcoma to treatment with trabectedin

Predictive biomarkers of trabectedin represent an unmet need in advanced soft‐tissue sarcomas (STS). DNA damage repair (DDR) genes, involved in homologous recombination or nucleotide excision repair, had been previously described as biomarkers of trabectedin resistance or sensitivity, respectively....

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Detalles Bibliográficos
Autores principales: Moura, David S., Peña‐Chilet, Maria, Cordero Varela, Juan Antonio, Alvarez‐Alegret, Ramiro, Agra‐Pujol, Carolina, Izquierdo, Francisco, Ramos, Rafael, Ortega‐Medina, Luis, Martin‐Davila, Francisco, Castilla‐Ramirez, Carolina, Hernandez‐Leon, Carmen Nieves, Romagosa, Cleofe, Vaz Salgado, Maria Angeles, Lavernia, Javier, Bagué, Silvia, Mayodormo‐Aranda, Empar, Vicioso, Luis, Hernández Barceló, Jose Emilio, Rubio‐Casadevall, Jordi, de Juan, Ana, Fiaño‐Valverde, Maria Concepcion, Hindi, Nadia, Lopez‐Alvarez, Maria, Lacerenza, Serena, Dopazo, Joaquin, Gutierrez, Antonio, Alvarez, Rosa, Valverde, Claudia, Martinez‐Trufero, Javier, Martín‐Broto, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637557/
https://www.ncbi.nlm.nih.gov/pubmed/33983674
http://dx.doi.org/10.1002/1878-0261.12996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637557/
https://www.ncbi.nlm.nih.gov/pubmed/33983674
http://dx.doi.org/10.1002/1878-0261.12996

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