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Overcoming the senescence‐associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer

Senescence is a cellular state in which cells undergo persistent cell cycle arrest in response to nonlethal stress. In the treatment of cancer, senescence induction is a potent method of suppressing tumour cell proliferation. In spite of this, senescent cancer cells and adjacent nontransformed cells...

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Detalles Bibliográficos
Autores principales:	Chambers, Cecilia R., Ritchie, Shona, Pereira, Brooke A., Timpson, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637570/ https://www.ncbi.nlm.nih.gov/pubmed/34137158 http://dx.doi.org/10.1002/1878-0261.13042

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