iRGD‐modified exosomes effectively deliver CPT1A siRNA to colon cancer cells, reversing oxaliplatin resistance by regulating fatty acid oxidation

Fatty acid oxidation (FAO) plays a vital role in drug resistance in cancer cells. Carnitine palmitoyltransferase 1A (CPT1A), a key enzyme of FAO, is widely recognized as an emerging therapeutic target. Here, we confirmed that CPT1A was heterogeneously expressed in colon cancer cells, with a high exp...

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Detalles Bibliográficos
Autores principales: Lin, Dan, Zhang, Haiyang, Liu, Rui, Deng, Ting, Ning, Tao, Bai, Ming, Yang, Yuchong, Zhu, Kegan, Wang, Junyi, Duan, Jingjing, Ge, Shaohua, Sun, Bei, Ying, Guoguang, Ba, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637580/
https://www.ncbi.nlm.nih.gov/pubmed/34213835
http://dx.doi.org/10.1002/1878-0261.13052

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