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Securing Native Disulfide Bonds in Disulfide-Coupled Protein Folding Reactions: The Role of Intrinsic and Extrinsic Elements vis-à-vis Protein Aggregation and Neurodegeneration
[Image: see text] Disulfide bonds play an important role in physiology and are the mainstay of proteins that reside in the plasma membrane and of those that are secreted outside the cell. Disulfide-bond-containing proteins comprise ∼30% of all eukaryotic proteins. Using bovine pancreatic ribonucleas...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637583/ https://www.ncbi.nlm.nih.gov/pubmed/34869967 http://dx.doi.org/10.1021/acsomega.1c05269 |